Acetylsalicylic acid,
Medication Facts
- Performance enhancing
- No
- Total hours to clear
- Not recorded
- Frequently used
- Most Prescribed
- ESC ID
- ACETYL-0023
- Trade names
- Bayer Aspirin
- Drug type
- NSAID, Cox2 Inhibitor
- Plasma half-life · hours
- 0.11 to 0.53
- Equine dosing
- 10-15 mg/kg PO
- Cmax · peak plasma concentration
- 300 µg/mL
- Tmax · time to peak plasma concentration
- 3
- ESC concentration guidance
- 300 mg/mL
- Primary withdrawal · hours
- 0
- Washout withdrawal · hours
- 0
- ESC control type
- A1 - Generally Controlled - Therapeutic
- Medication report required
- Generally not required, however understand exceptions.
Uses & side effects
Inhibits COX Production (COX inceptors cause inflamation/fever)
Drug interactions
Using more than one NSAID concurrently (e.g., combining phenylbutazone, flunixin meglumine, or firocoxib) drastically increases risks of toxicity without increasing pain relief.Corticosteroids (e.g., Dexamethasone): Combining NSAIDs with steroids increases the likelihood of gastric ulcers and severe GI toxicity.Nephrotoxic Agents: Avoid combining NSAIDs with aminoglycoside antibiotics (e.g., gentamicin) or diuretics, as this significantly increases the risk of acute renal failure.Blood Thinners: Concomitant use with anticoagulants (e.g., heparin) increases the risk of bleeding complications.Dehydration/Pre-existing Disease: NSAIDs are more toxic when horses are dehydrated, septic, or have pre-existing kidney or hepatic disease
Contraindications
None currently identified.