Anisotropine
Medication Facts
- Performance enhancing
- No
- Total hours to clear
- Not recorded
- Frequently used
- N/A
- ESC ID
- ANISOT-0076
- Trade names
- Not recorded
- Drug type
- Anticholinergic
- Plasma half-life · hours
- Not Published
- Equine dosing
- Consult Veternarian
- Cmax · peak plasma concentration
- Unavailable
- Tmax · time to peak plasma concentration
- Unavailable
- ESC concentration guidance
- May not exceed 6% of efficacy in plasma
- Primary withdrawal · hours
- 12
- Washout withdrawal · hours
- 0
- ESC control type
- A1 - Generally Controlled - Therapeutic
- Medication report required
- Generally not required, however understand exceptions.
Uses & side effects
Product-specific side effects await source review.
Drug interactions
anticholinergic drugs in horses are used primarily to reduce smooth muscle spasms, decrease secretions, dilate the pupils, and modify gastrointestinal or respiratory activity. They work by blocking acetylcholine at muscarinic receptors.
Common equine anticholinergic drugs include:
Atropine
Scopolamine (hyoscine)
Glycopyrrolate
N-butylscopolammonium bromide
Common Uses in Horses
Gastrointestinal spasms / colic
The most common use is:
treatment of spasmodic colic
reducing intestinal cramping
rectal relaxation during examination
N-butylscopolammonium bromide is widely used for:
spasmodic colic
intestinal hypermotility
facilitating rectal exams
Ophthalmic use
Atropine is commonly used:
to dilate the pupil
relieve painful eye spasms in uveitis (“moon blindness”)
prevent ocular adhesions
Anesthesia and respiratory management
Glycopyrrolate or atropine may be used:
to reduce salivation and airway secretions
to prevent vagal bradycardia during anesthesia