Bromfenac
Medication Facts
- Performance enhancing
- No
- Total hours to clear
- Not recorded
- Frequently used
- Most Prescribed
- ESC ID
- BROMFE-0135
- Trade names
- Duract
- Drug type
- NSAID
- Plasma half-life · hours
- 2 hrs
- Equine dosing
- 0.07% to 0.09%, **administered to eye, the drug penetrates the cornea rapidly to reach therapeutic peak levels**
- Cmax · peak plasma concentration
- 242 ng/mL
- Tmax · time to peak plasma concentration
- 3 hrs
- ESC concentration guidance
- 242 ng/mL
Limit of detection is 0.242 ng/mL - Primary withdrawal · hours
- 0
- Washout withdrawal · hours
- 0
- ESC control type
- A1 - Generally Controlled - Therapeutic
- Medication report required
- Generally not required, however understand exceptions.
Uses & side effects
Pain & Inflamation Relief Eyes - Post Surgical
Product-specific side effects await source review.
Drug interactions
Using more than one NSAID concurrently (e.g., combining phenylbutazone, flunixin meglumine, or firocoxib) drastically increases risks of toxicity without increasing pain relief.Corticosteroids (e.g., Dexamethasone): Combining NSAIDs with steroids increases the likelihood of gastric ulcers and severe GI toxicity.Nephrotoxic Agents: Avoid combining NSAIDs with aminoglycoside antibiotics (e.g., gentamicin) or diuretics, as this significantly increases the risk of acute renal failure.Blood Thinners: Concomitant use with anticoagulants (e.g., heparin) increases the risk of bleeding complications.Dehydration/Pre-existing Disease: NSAIDs are more toxic when horses are dehydrated, septic, or have pre-existing kidney or hepatic disease