Carprofen
Medication Facts
- Performance enhancing
- No
- Total hours to clear
- Not recorded
- Frequently used
- N/A
- ESC ID
- CARPRO-0186
- Trade names
- Rimadyl
- Drug type
- NSAID
- Plasma half-life · hours
- Not Published
- Equine dosing
- 1-2 mg/kg PO
- Cmax · peak plasma concentration
- 10 µg/mL
- Tmax · time to peak plasma concentration
- 45
- ESC concentration guidance
- May not exceed 6% efficacy in plasma
- Primary withdrawal · hours
- 12
- Washout withdrawal · hours
- 0
- ESC control type
- A1 - Generally Controlled - Therapeutic
- Medication report required
- Generally not required, however understand exceptions.
Uses & side effects
Product-specific side effects await source review.
Drug interactions
Using more than one NSAID concurrently (e.g., combining phenylbutazone, flunixin meglumine, or firocoxib) drastically increases risks of toxicity without increasing pain relief.Corticosteroids (e.g., Dexamethasone): Combining NSAIDs with steroids increases the likelihood of gastric ulcers and severe GI toxicity.Nephrotoxic Agents: Avoid combining NSAIDs with aminoglycoside antibiotics (e.g., gentamicin) or diuretics, as this significantly increases the risk of acute renal failure.Blood Thinners: Concomitant use with anticoagulants (e.g., heparin) increases the risk of bleeding complications.Dehydration/Pre-existing Disease: NSAIDs are more toxic when horses are dehydrated, septic, or have pre-existing kidney or hepatic disease