Medication Facts
- Performance enhancing
- N/A
- Total hours to clear
- N/A
- Frequently used
- Not recorded
- ESC ID
- COLIC-0247
- Trade names
- Not recorded
- Drug type
- N/A
- Plasma half-life · hours
- N/A
- Equine dosing
- N/A
- Cmax · peak plasma concentration
- N/A
- Tmax · time to peak plasma concentration
- N/A
- ESC concentration guidance
- N/A
- Primary withdrawal · hours
- N/A Banned
- Washout withdrawal · hours
- Not recorded
- ESC control type
- N/A
- Medication report required
- N/A
Uses & side effects
Colic
Product-specific side effects await source review.
Drug interactions
1. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)NSAIDs reduce inflammation and deliver long-lasting pain relief, but they can mask symptoms if given too early.Flunixin Meglumine (Banamine): The gold standard for colic. It relieves mild to moderate pain for 8–12 hours and binds to harmful endotoxins in the bloodstream. It must always be given intravenously (IV) or orally—never intramuscularly (IM), as this can cause fatal tissue infections.Firocoxib (Equioxx): A newer, selective NSAID that targets pain while sparing the stomach lining, making it safer for the horse's gut.Phenylbutazone (Bute): More commonly used for bone and joint pain, but occasionally used if flunixin is unavailable.2. Sedatives and Alpha-2 AgonistsVets use these short-acting drugs for intense pain or to safely sedate an unmanageable horse for a physical exam.Xylazine (Rompun): Provides powerful, immediate pain relief and muscle relaxation lasting 20–30 minutes.Detomidine (Dormosedan): Similar to xylazine but much stronger and longer-lasting.3. Spasmolytics (Antispasmodics)Buscopan (N-butylscopolamine): Used specifically for spasmodic (gas) colic. It stops severe intestinal cramping and spasms by relaxing the smooth muscles of the digestive tract. It also temporarily raises the heart rate, which the vet will factor into their exam.4. Controlled Analgesics (Opioids)When a horse suffers from severe, refractory pain (such as a twisted bowel), NSAIDs alone are not enough.Butorphanol (Torbugesic): A narcotic pain reliever typically mixed directly with xylazine or detomidine to maximize pain control without causing dangerous excitement.5. Laxatives and Gastrointestinal LubricantsWhile technically therapies rather than systemic medications, these are administered directly into the stomach through a nasogastric tube to clear blockages:Mineral Oil: Lubricates the intestinal tract to help pass dry impactions.Epsom Salts (Magnesium Sulfate): Acts as an osmotic laxative, drawing water into the GI tract to soften impacted feed.