Equine Sports Council

Controlled Medications Library

ESC MEDICATION CLASSIFICATIONClass A - Therapeutic

ESC Medication Library · Revision 2

← Medication library · Compare sanctioning bodies

Medication Facts

Performance enhancing
Potentially
Total hours to clear
504
Frequently used
Most Prescribed
ESC ID
CORTIS-0251
Trade names
Not recorded
Drug type
Corticosteroid
Plasma half-life · hours
Not Published
Equine dosing
Consult Veterinarian, consult a licensed veterinarian to discuss treatment options before combining with with corticosteroids or NSAIDS, caution using with other substances
Cmax · peak plasma concentration
0.3 µg/mL
Tmax · time to peak plasma concentration
3
ESC concentration guidance
72 HR WD 1 mcg/mL, 7 Days undectectable
Primary withdrawal · hours
72
Washout withdrawal · hours
168
ESC control type
A1 - Generally Controlled - Therapeutic
Medication report required
Generally not required, however understand exceptions.

Uses & side effects

Product-specific side effects await source review.

Drug interactions

Corticosteroids in horses (e.g., dexamethasone, prednisolone) interact significantly with NSAIDs, increasing gastrointestinal ulceration risk. They also interact with diuretics (furosemide) causing severe potassium depletion, and with vaccines, as immune suppression reduces vaccine efficacy. Use caution with insulin, as steroids increase blood glucose and risk laminitis.

Contraindications

Sanctioning-body comparison

Plasma only. Compare published competition guidance for this medication. ESC guidance remains in Medication Facts above. A dosing guideline, withdrawal recommendation and laboratory detection threshold are different measures.

Sources reviewed September 23, 2026. “Not verified” means a gap in this comparison, not zero tolerance or permission. Doses describe the cited rules; your veterinarian must determine treatment and withdrawal.

Published guidance by organization
OrganizationPublished dose & routePlasma concentrationWithdrawal / timingControl / penalty class
AQHA Show HorsesShow rules · 2026 handbook
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
APHA Paint Show HorsesShow rules · 2026 Rule Book
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
ARCI Model RulesRacing model · Rules 15 / UCG 20.0 / CTMS 4.2.1
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules. ARCI model comparison only; no state-specific rule is substituted. Schedule timing is tied to its stated regimen and is not a clearance guarantee.

UCG 20.0 PDF p. 22

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Drug Class 4 · Penalty Class C. No dosing permission is implied by classification.
USEFNational Therapeutic Substance Provisions · 2026 + July amendment
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.