Equine Sports Council

Controlled Medications Library

ESC Medication Library · Revision 2

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Medication Facts

Performance enhancing
N/A
Total hours to clear
N/A
Frequently used
Not recorded
ESC ID
EYE-0382
Trade names
Not recorded
Drug type
N/A
Plasma half-life · hours
N/A
Equine dosing
N/A
Cmax · peak plasma concentration
N/A
Tmax · time to peak plasma concentration
N/A
ESC concentration guidance
N/A
Primary withdrawal · hours
N/A
Washout withdrawal · hours
Not recorded
ESC control type
N/A
Medication report required
N/A

Uses & side effects

Eye

Product-specific side effects await source review.

Drug interactions

Equine eye medications (ophthalmic therapies) are strictly categorized by their function to treat corneal ulcers, manage intraocular inflammation, alleviate deep ocular pain, or target fungal infections.Because topical medications are readily absorbed into the bloodstream via the highly vascular conjunctiva and the nasolacrimal (tear) duct, many ophthalmic medications are regulated or prohibited under USEF, FEI, and HISA competition guidelines.Ophthalmic AntibioticsUsed to treat or prevent bacterial infections, primarily secondary to corneal ulcers or scratches.Triple Antibiotic (BNP) (Bacitracin, Neomycin, Polymyxin B): The standard first-line ointment for simple, non-infected corneal ulcers.Tobramycin / Gentamicin: Aminoglycoside drops utilized for aggressive, severe, or Gram-negative bacterial infections.Chloramphenicol: A highly penetrative ointment favored for deep stromal ulcers because it crosses the cellular barriers of the cornea efficiently.Ophthalmic Anti-Inflammatories & CorticosteroidsUsed to combat intraocular inflammation, such as Equine Recurrent Uveitis (ERU / Moon Blindness).NeoPolyDex (NPD) (Neomycin, Polymyxin B, Dexamethasone): A highly potent combination of antibiotics and a corticosteroid.Flurbiprofen / Diclofenac: Topical Non-Steroidal Anti-Inflammatory (NSAID) drops used to manage surface or intraocular inflammation.⚠️ Strict Contraindication: Corticosteroids (like Dexamethasone or Prednisolone) must NEVER be administered to a horse with a corneal ulcer. Doing so blocks corneal healing, suppresses the local immune response, and can lead to rapid melting or rupture of the eye.Regulatory Note: Topical corticosteroids and NSAIDs absorb systemically and can trigger a positive drug test if not withdrawn or declared properly.Mydriatics & Cycloplegics (Pain Relief)Used to dilate the pupil and paralyze the painful spasming of the ciliary muscle inside the eye.Atropine Sulfate (1%): The gold standard for controlling deep, structural eye pain associated with uveitis or severe corneal ulcers.Clinical Caution: Atropine slows down gastrointestinal motility through systemic absorption. Horses on frequent atropine drops must be monitored carefully for signs of colic.Antifungals & AntiproteasesUsed for "melting" or complicated ulcers where environmental fungi or destructive tissue enzymes are destroying the cornea.Voriconazole / Miconazole: Compounded antifungal medications essential for treating equine keratomycosis (fungal corneal infections).Autologous Serum: The horse's own blood is drawn, spun down, and the serum is applied topically to the eye. Serum contains natural antiproteases that stop the "melting" enzymatic destruction of the cornea.

Contraindications

Sanctioning-body comparison

Plasma only. Compare published competition guidance for this medication. ESC guidance remains in Medication Facts above. A dosing guideline, withdrawal recommendation and laboratory detection threshold are different measures.

Sources reviewed September 23, 2026. “Not verified” means a gap in this comparison, not zero tolerance or permission. Doses describe the cited rules; your veterinarian must determine treatment and withdrawal.

Published guidance by organization
OrganizationPublished dose & routePlasma concentrationWithdrawal / timingControl / penalty class
AQHA Show HorsesShow rules · 2026 handbook
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
APHA Paint Show HorsesShow rules · 2026 Rule Book
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
ARCI Model RulesRacing model · Rules 15 / UCG 20.0 / CTMS 4.2.1
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
USEFNational Therapeutic Substance Provisions · 2026 + July amendment
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.