Isoxsuprene
Medication Facts
- Performance enhancing
- No
- Total hours to clear
- Not recorded
- Frequently used
- Most Prescribed
- ESC ID
- ISOXSU-0481
- Trade names
- Isoxsuprene
- Drug type
- Vasodialator
- Plasma half-life · hours
- 3
- Equine dosing
- 1.2 to1.8 mg per kg of body weight for treatment of Navicular hoof disease
- Cmax · peak plasma concentration
- Not recorded
- Tmax · time to peak plasma concentration
- Not recorded
- ESC concentration guidance
- CMAX 100% of Efficacy
- Primary withdrawal · hours
- 0
- Washout withdrawal · hours
- 0
- ESC control type
- A1 - Generally Controlled - Therapeutic
- Medication report required
- Generally not required, however understand exceptions.
Uses & side effects
Promotes Blood Flow to Hooves & Uterous
Drug interactions
Human drug not approved for use in equines, However widely prescribed in horses by vets to treat navicular. Isoxsuprene when given orally has poor absorption through the GI tract of horses and is not recommended. Drug interactions with oral isoxsuprine are generally considered unlikely due to the drug's extremely low absorption in the equine digestive tract. However, isoxsuprine acts as a vasodilator, and veterinarians must be notified if it is being used alongside sedatives, anesthetics, narcotics, or other blood pressure-altering medications to avoid adverse cardiovascular events.Because of its specific pharmacological properties, isoxsuprine carries notable interactions and administration considerations:Anesthetics and Tranquilizers: Combining isoxsuprine with systemic anesthetics or tranquilizers can lead to severe or unintended hypotension (low blood pressure) and tachycardia (increased heart rate). Always clear concurrent use with a veterinarian.Vasodilators and Beta-Blockers: Concomitant use with other vasodilators or certain cardiovascular drugs may potentiate blood pressure drops.Bleeding and Foaling: Isoxsuprine should not be administered to horses that are actively bleeding or to mares immediately following foaling