Equine Sports Council

Controlled Medications Library

ESC Medication Library · Revision 2

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Medication Facts

Performance enhancing
N/A
Total hours to clear
N/A
Frequently used
Not recorded
ESC ID
ASTHMA-0088
Trade names
Not recorded
Drug type
N/A
Plasma half-life · hours
N/A
Equine dosing
N/A
Cmax · peak plasma concentration
N/A
Tmax · time to peak plasma concentration
N/A
ESC concentration guidance
N/A
Primary withdrawal · hours
N/A Banned
Washout withdrawal · hours
Not recorded
ESC control type
N/A
Medication report required
N/A

Uses & side effects

Asthma Breathing

Product-specific side effects await source review.

Drug interactions

Corticosteroids and bronchodilators form the core of medical therapy for equine asthma (formerly known as heaves, RAO, or IAD). While bronchodilators temporarily open narrowed airways to give a horse immediate physical relief, corticosteroids are the actual mainstay of treatment because they reduce the underlying lung inflammation.Veterinarians prescribe these medications across two primary categories and deliver them either systemically (orally/injectable) or via inhalation devices.1. Corticosteroids (Anti-Inflammatories)These target lung inflammation, swelling, and mucus production. They are mandatory for long-term management, as bronchodilators alone will stop working if inflammation is left unchecked.Dexamethasone: A highly potent, fast-acting systemic steroid given orally or by intravenous (IV) injection. It is highly effective for severe flare-ups, but long-term use carries a risk of inducing laminitis.Prednisolone: An oral systemic steroid tablet or powder typically used for daily maintenance or tapering protocols. It is generally considered safer for prolonged use than dexamethasone.Fluticasone propionate (Flovent): An inhaled corticosteroid administered through an equine-specific mask and spacer. It delivers targeted relief directly to the lungs, dramatically minimizing the risk of systemic side effects like laminitis.Ciclesonide (Aservo Equihaler): An FDA-approved inhaled prodrug designed specifically for horses. It remains inactive until it reaches the lower respiratory tract, further lowering the risk of systemic complications.2. Bronchodilators (Airway Openers)These relax the smooth muscles surrounding the airways to ease breathing quickly during a spasm, but they do not cure the underlying inflammation.Clenbuterol hydrochloride (Ventipulmin): An oral syrup that acts as a beta-2 agonist to relax the airways. While highly effective for short-term relief, horses can develop a tolerance (tachyphylaxis) if it is used continuously for more than a few weeks.Albuterol (Salbutamol): A short-acting, rapid inhaled bronchodilator administered via a mask. It takes effect within 5 minutes and is used primarily as a "rescue" medication for immediate relief during an active breathing crisis.Ipratropium bromide (Atrovent): An inhaled anticholinergic drug used to block the nerve signals that cause airway constriction. It provides longer-lasting airway dilation than albuterol and is often paired with it.3. Emergency Rescue MedicationsIf a horse is in a life-threatening, acute asthmatic crisis where it cannot draw breath, a veterinarian may administer immediate intravenous medications:Buscopan (Butylscopolammonium bromide) or Atropine: These IV anticholinergic drugs can rapidly break a severe lung spasm within minutes, though they carry side effects like an elevated heart rate or a temporary risk of colic.⚠️ Critical Reminder: No medication will successfully treat equine asthma without strict environmental management. Medical therapies are easily overwhelmed if a horse remains in a dust-filled barn, eats dry or round-bale hay, or sleeps on dusty straw bedding.Is your horse experiencing an acute breathing emergency right now, or are you looking to establish a long-term management plan for a diagnosed horse? If you are considering an inhalation mask (like an AeroHippus), I can provide details on how to condition your horse to accept it.This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more33 sitesAsthma in Horses - Respiratory SystemFeb 15, 2026 — Treatment of Asthma in Horses * For severely-affected horses, asthma is a lifelong disease. The goals for treatment are to control...MSD Veterinary ManualCommon Medications Used for Treatment of Equine AsthmaCommon Medications Used for Treatment of Equine Asthma ; Ipratropium bromide: 0.18 – 0.3 mg per horse, inhaled via an equine-speci...Merck Veterinary ManualHow to Best Manage and Treat Equine Asthma - FVMASep 6, 2024 — Some drugs used to treat equine asthma include: * **Dexamethasone** * **Prednisolone** * **Clenbuterol hydrochloride syrup** * **A...

Contraindications

Sanctioning-body comparison

Plasma only. Compare published competition guidance for this medication. ESC guidance remains in Medication Facts above. A dosing guideline, withdrawal recommendation and laboratory detection threshold are different measures.

Sources reviewed September 23, 2026. “Not verified” means a gap in this comparison, not zero tolerance or permission. Doses describe the cited rules; your veterinarian must determine treatment and withdrawal.

Published guidance by organization
OrganizationPublished dose & routePlasma concentrationWithdrawal / timingControl / penalty class
AQHA Show HorsesShow rules · 2026 handbook
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
APHA Paint Show HorsesShow rules · 2026 Rule Book
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
ARCI Model RulesRacing model · Rules 15 / UCG 20.0 / CTMS 4.2.1
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.
USEFNational Therapeutic Substance Provisions · 2026 + July amendment
Conditions & sources

An unverified entry is not permission to use this medication. Consult the linked current rules.

Reviewed 2026-09-23

Not verified for this medication.Not verified for this medication.Not verified for this medication.Medication-specific control not yet verified.